I purchased the Navigon 2100 back in March and used it on a trip to Florida for Spring Break. I was for the most part impressed, especially for the $119.00 on sale I paid for it at Staples. The spoken road names feature is very nice, although sometimes the pronunciation is, uhmm interesting. The "Reality View" of complicated exits is an outstanding feature. I was amazed over and over again about how much data that is loaded on a single SD card.
Sometimes the route the GPS chose didn't seem to always be the most logical route, even though there are several settings to choose the "fastest" "shortest", etc. For example, on a Florida freeway it wanted me to take an obvious exit to the left and immediately merge back onto the same freeway. I'm guessing it calculated that as the shortest route? Also the number of POI's included are not that impressive. It had some gas stations, restaurants & rest areas listed, but overall POI's are pretty sparse.
If you just want a GPS that will get you from Point A to Point B, the Navigon 2100 does a fine job and gives good peace of mind that you won't get lost. If you need a GPS that will be able to locate a specific restaurant by name, you might want to consider another model/brand.
Hope that helps.