I checked just now, and my 622 with L443 still has guide info for all digital subchannels it can receive (2, 7, 16, 22, 26, 45).
My 222 with L301 still has guide info for 2, 7, 16, 22, and 26, but no info for 45 (and of course no info for 43.x, the additional stations it can receive that the 622 cannot).