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In no way can the varietal colors and hues of various channels be blamed on the Hopper. There are few if any camera calibration standards amongst networks and production companies. Multi-camera sports is a prime example of non-balanced and leveled cameras. Wide shots might look "real", while tighter and close-ups can run the gamut of color hues. And is this digital age, colors and light levels, even image clarity tend to get overly manipulated
I would suggest to the TS, that you do not rely on CNN as your base standard. Overly soft and flat studio lighting, contrasted to harsher location lighting are not conducive to realistic "calibration". If there is one channel I believe has the most consistent and pleasing tonality, is the Cooking Channel. And as MikeD pointed out, each TV manufacturer seem to "push" one color more than another, though I have to disagree with him over his opinion of Samsung. I spent 15 years in 35/16mm film, and broadcast video production. That experience built the cornerstone of my "video quality" perception(s).

If you have not done it, go to AvsForum find your model thread and see what has been posted for settings from people who actually calibrated theirs. It won't be 100% like having an expert come to your house, but it will be darn close. If those settings make the TV look alot different take time to get used to it before deciding you don't like them because unless you got lucky those will be vastly better than your guessing at what looks good by using a particular channel.
The fact that you are making settings based on one particular channel instead of actually calibrating the TV itself explains alot of the problem.
Skip the Denon for now both because that has to be eliminated as the problem and because you should calibrate the TV after getting the calibration settings without it first. Be sure your HDMI cables are in good shape and connected firmly. If you have one to swap with, try changing the one from the Hopper to the TV. If it is a 4K TV be sure UHD Color for HDMI inputs is turned off for any input not in 4K. Most all settings "enhancements" make the picture worse and you will see most suggested calibrations from those who used calibration tools will have them all or almost all off.

Some channels and even some programs on some channels look different. USA is a terrific example. Reruns of some shows like NCIS (Already shot with extreme softness in many scenes) or Law and Order often look old, maybe washed out while other shows or USA originals look very good. Live with Kelly looks the same in Ct on that local station as it does in Tampa on that local station - Horrible. The colors are off and it is washed out or just looks weird compared to most other shows.
Finally some shows have more color saturation than others, one good example is CBS This Morning, and many times local live news programs. (Which can look a little different from each other)

Go to avs and download the calibration files and use those to set the tv up somewhat properly, then you can make adjustments for various sources.

Thanks for that confirmation of what I suspected on the production side. I've used a few other channels and seem to have dialed it in as best I can but there are still differences of hue, color temp, etc etc. I'll admit I'm an AV perfectionist and am not very tolerant of poor quality audio or video. I wish it didn't bother me so much. Sounds like I have some more research to do on AVS.

Yes, I have noticed it. Just switched from HWS to H3, same TV, and while it shouldn't have made a difference, to me it did. I spent a lot of time adjusting the picture (and learning the box) but when I changed channels it would be off, mostly in the faces, but other places too. I finally adjusted to channels I watch a lot and try to ignore it on the others. Skin tones on Fox News look off, may have to do more adjusting