Run Disk Defragmentation, too, as that will help programs load faster off the disk. (right-mouse-click on your disk icon, select Properties from the pop-up menu, click on the "Tools" tab, and select the Defragment tool)
As an old VMS guy, I always set the size of my Page file on the system to as big as I can. With disk drives pushing 1 TB, what's 2 or 4 GB for a page file? By default, Windows will say something like minimum - maximum size. What that does is cause fragmentation when Windows needs to enlarge the paging file. If you set both the min and max sizes the same, to at least the same size as the amount of RAM you have (I like using twice as much) then Windows has enough to do a full memory dump if it BSODs.
You should defrag the disk before extending the Page file, and to do it right, configure your system to run without the page file, reboot, defrag, set the fixed page file to 2x RAM, reboot, and defrag one last time. But that's just me.
If you spend $$$ on Diskeeper, you can run the Defragger on a scheduled basis and also do boot-time defragmentation which allows all the files to be consolidated, even those that Windows normally have open.