Do you mean from the serial port of your notebook to the receiver? There are no tools that I know of that do anything interesting via the serial port besides up/download firmware & channel/sat info.
TSReader generally requires a tuner device for the PC. Either a PCI/PCIe card or a USB tuner. It will also talk to some things across a network, but typically you need a local device.
What are you thinking about for this software? Remotely controlling tuning or something similar?