Both direct, and the indirect stuff that doesn't get included in the suicide stats.
My sisters mother-in-law died 3 months after refusing further chemo treatment.
My own mother in law refused food and fluids, causing her body to shut down.
After watching my wife die a slow and painful death from cancer, I don't know how I would handle a diagnosis these days. I know that I would not be as agressive on treatment as we were for her. She wanted to keep fighting, and we did, but I feel that I didn't do her any favors by not letting her go during a crisis two years earlier.