I actually broke down and bought a Harmony 650 to try out. At $39.99 it's not an expensive experiment. I need it to work with my Panny Plasma TV, my Hopper 3, my Sony AVR, and my Roku Utra (don't need it to work with my PS4.)
Since I have a Roku Ultra and a TV and AVR and 4K Joey in my other two rooms, if it works well in the room with the Hopper 3 I'll just get one for each room (my wife wants to learn ONE remote.

)
I assume I'll keep my 40s with good batteries in the rooms, as I assume the H3 won't back up it's settings to the Harmony like it does the Dish remotes.